Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Size:5mg CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCN2CCNCC2)C(C)(C)C)C=C1 Purity (HPLC) >= 95%

CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCN2CCNCC2)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name CA-DBCO Synonyms HaloTag DBCO Ligand

making it highly suitable for live-cell imaging and other biological applications

351 SMILES CC(C)(C)OC(=O)CN1CCN(CCN)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Size:5mg CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCN2CCNCC2)C(C)(C)C)C=C1 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent